2025 College Football Schedule Week 1 Predictions. Here are the storylines to know, matchups to watch and predictions for the five biggest games of week 1. Top matchups of the week include georgia vs clemson and colorado vs north dakota state.

A closer look at the top games that will kick off week 1 of the 2025 college football season. Let’s take a look at our expert picks for the best games in week 1.